Pro-Nox

The Pain-Free, Anxiety-Free Treatment Experience You Deserve

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  • ExpertiseTop 1%Injector in the country
  • ExperienceOver 11,000Patients treated
  • Excellence590+Five star reviews

Why Choose Dr. Avaliani for the Pro-Nox Experience?

Dr. Avaliani believes every aesthetic treatment should be comfortable and anxiety-free. Pro-Nox is a self-administered nitrous oxide system that delivers a 50/50 blend of nitrous oxide and oxygen, allowing patients to relax, reduce anxiety, and eliminate discomfort during any cosmetic procedure. Available for every treatment at no mandatory upcharge: it is the foundation of the Dr. Avaliani Experience.

  • Self-Administered Comfort

    You control your own comfort level with a simple mouthpiece: breathe in when you want relief, stop when you feel comfortable

  • Board-Certified Physician

    11+ years of experience ensuring patient comfort and safety during every treatment

  • Universal Compatibility

    Pro-Nox can be used with virtually any treatment, from BOTOX and fillers to lasers, body contouring, and thread lifts

  • A Reputation Built on Results

    5.0-star rating with 565+ verified reviews emphasizing the comfort of the treatment experience

  • Zero Recovery Time

    Effects wear off completely in under 10 minutes. You can drive yourself home and return to all normal activities immediately Dr. Avaliani will discuss Pro-Nox with you during your consultation to ensure your treatment experience is as comfortable and anxiety-free as possible.

What Is Pro-Nox?

Pro-Nox is a patient-controlled inhaled analgesia system that delivers a fixed 50/50 mixture of nitrous oxide and oxygen gas. It provides immediate anxiety relief and pain reduction during cosmetic procedures without sedation, needles, or opioids. The patient self-administers through a disposable mouthpiece, controlling exactly how much comfort they need at any moment.

At Dr. Avaliani’s practice, Pro-Nox is the cornerstone of the comfort experience. It works within 2-3 minutes of inhalation, producing slight euphoria and deep relaxation that reduces pain perception through analgesia, not full anesthesia. You remain fully awake, alert, and in control throughout your treatment.

How Pro-Nox Works

The Pro-Nox experience is simple and patient-controlled:

  • A disposable mouthpiece is provided. You breathe normally through it whenever you want comfort
  • The fixed 50/50 nitrous oxide and oxygen blend takes effect within 2-3 minutes
  • You experience gentle euphoria and relaxation, reducing anxiety and pain perception
  • You control the intensity by breathing in more or less through the mouthpiece
  • Effects wear off completely within 10 minutes after you stop breathing through the mouthpiece, no lingering drowsiness

Treatments Enhanced by Pro-Nox

  • Injection Anxiety

    Nervous about needles? Pro-Nox calms anxiety before BOTOX, Dysport, and dermal filler injections, making the experience comfortable and stress-free.

  • Laser Treatment Comfort

    Laser procedures like PicoSure, tattoo removal, and skin resurfacing are more comfortable with Pro-Nox reducing pain perception during treatment.

  • Body Contouring Sessions

    Longer procedures like CoolSculpting, SculpSure, and Emsculpt NEO are more relaxing with Pro-Nox available throughout your session.

  • Microneedling & RF

    Microneedling, Genius RF, and Morpheus8 treatments involve micro-pinprick sensations that Pro-Nox effectively minimizes for a comfortable experience.

  • Thread Lift Procedures

    PDO thread lifts involve multiple insertion points. Pro-Nox provides continuous comfort control throughout the entire procedure.

  • First-Time Patients

    If you’ve never had an aesthetic treatment before, Pro-Nox eliminates the fear of the unknown, making your first experience positive and anxiety-free.

Our Comfort Technologies

Dr. Avaliani offers multiple comfort technologies to ensure every treatment is a positive experience. Here’s what sets her practice apart:

  • Pro-Nox™ System

    The leading patient-controlled nitrous oxide delivery system. Fixed 50/50 N₂O/O₂ blend via disposable mouthpiece. Self-administered, non-addictive, FDA-cleared. Effects in 2-3 minutes, gone in under 10. Used with any cosmetic procedure.

  • NitroNox™ System

    Identical gas delivery mechanism to Pro-Nox: same 50/50 nitrous oxide and oxygen blend via patient-controlled disposable mouthpiece. Both systems provide the same comfort experience.

  • AccuVein® Technology

    Advanced vein visualization complements Pro-Nox for the ultimate comfort experience. AccuVein maps blood vessels in real time to virtually eliminate bruising during all injection procedures.

Call us today to schedule your consultation with Dr. Avaliani and experience the comfort of Pro-Nox during your next treatment!

Does It Hurt?

Your comfort options (we tailor this to you)

Pro-Nox IS the comfort solution. When using Pro-Nox during your treatment, most patients describe the experience as completely comfortable, even relaxing. The nitrous oxide creates a gentle sense of euphoria that significantly reduces pain perception without sedation. You remain fully aware and in control throughout.

Pro-Nox itself requires zero recovery time. All effects wear off within 10 minutes after you stop breathing through the mouthpiece. You can drive yourself home, return to work, and resume all normal activities immediately. No designated driver needed.

Feel Calm. Stay in Control. Look Amazing.

Learn about your comfort options ›
  • Reduced anxietySettle into a calm, relaxed state before and during your treatment, with no stress and no tension.
  • Less discomfortEnhanced comfort for your treatment, so you can focus on your results.
  • No downtimeWalk out feeling great and drive yourself home. No recovery time required.

Is Pro-Nox Right for Me?

Ideal Candidates

You may be a good candidate if you:

  • Experience anxiety about needles or cosmetic procedures
  • Want maximum comfort during injectable treatments
  • Are undergoing longer procedures like laser treatments or body contouring
  • Prefer to avoid oral medications or opioids for comfort
  • Want to remain fully awake and in control during treatment
  • Are a first-time patient wanting a positive, stress-free introduction

What Does Pro-Nox Cost?

  • Pricing Information

    Pro-Nox is available as an add-on to any treatment. Pricing varies: ask about Pro-Nox when scheduling your appointment. Price Range: Many patients find it invaluable for their comfort and continue requesting it for every visit During your consultation, Dr. Avaliani will discuss Pro-Nox availability and pricing so you can make an informed decision about your comfort during treatment.

View before & after gallery

Results vary from patient to patient. The gallery shows real outcomes from treatments performed by Dr. Avaliani.

Before and after imagery to be added for this treatment.

Pro-Nox frequently asked questions

  • What is Pro-Nox?

    Pro-Nox is a patient-controlled nitrous oxide and oxygen system that delivers a fixed 50/50 blend. You self-administer through a disposable mouthpiece for immediate comfort during any cosmetic procedure. It provides anxiety relief and pain reduction without sedation.

  • Is Pro-Nox safe?

    Yes. Pro-Nox is FDA-cleared and used worldwide. The fixed 50/50 nitrous oxide and oxygen ratio prevents over-administration. It is non-addictive, and the patient controls their own intake at all times. Millions of treatments have been performed safely.

  • Can I drive after Pro-Nox?

    Yes. All effects of Pro-Nox wear off completely in under 10 minutes after you stop breathing through the mouthpiece. No designated driver is needed. You can drive yourself home and return to all normal activities immediately.

  • What procedures can use Pro-Nox?

    Virtually all aesthetic procedures: BOTOX, Dysport, dermal fillers, laser treatments, body contouring (CoolSculpting, SculpSure, Emsculpt NEO), microneedling, Genius RF, Morpheus8, PDO thread lifts, tattoo removal, and more.

  • Does Pro-Nox make you unconscious?

    No. Pro-Nox provides analgesia (pain reduction) and anxiolysis (anxiety relief), not sedation. You remain fully awake, alert, and in control throughout your entire treatment. It simply reduces pain perception and calms anxiety.

  • How quickly does Pro-Nox work?

    Effects begin within 2-3 minutes of inhalation through the mouthpiece. You will feel a gentle sense of relaxation and euphoria that reduces both anxiety and pain perception during your treatment.

  • Are there side effects?

    Pro-Nox is generally very safe. Some patients may experience mild nausea if they have not eaten before their appointment. Dr. Avaliani recommends eating a light meal before your visit to minimize this possibility.

  • Who cannot use Pro-Nox?

    Patients with a known allergy to nitrous oxide, certain respiratory conditions, ear infections, recent eye surgery involving intraocular gas, or pregnancy should not use Pro-Nox. Dr. Avaliani will review your medical history during consultation.

  • Is Pro-Nox the same as dental laughing gas?

    Similar concept, but Pro-Nox is specifically designed for aesthetic procedures. It uses a fixed 50/50 nitrous oxide and oxygen ratio with patient self-administration via a disposable mouthpiece, giving you full control over your comfort level.

  • What is the difference between Pro-Nox and NitroNox?

    They are identical systems from different manufacturers. Both deliver the same 50/50 nitrous oxide and oxygen blend via a patient-controlled disposable mouthpiece. The comfort experience is exactly the same regardless of which system is used.

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30 East 60th Street, Suite 1100New York, NY, 10022(btw Park & Madison Ave)
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212-673-8888

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