Alloclae

Next-Generation PLLA Biostimulation for Gradual, Natural Collagen Restoration

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  • ExpertiseTop 1%Injector in the country
  • ExperienceOver 11,000Patients treated
  • Excellence590+Five star reviews

Why Choose Dr. Avaliani for Alloclae?

Alloclae (AestheFill) is a next-generation poly-L-lactic acid (PLLA) biostimulator that gradually rebuilds your body’s own collagen for natural-looking volume restoration. Unlike traditional fillers that simply add volume, Alloclae stimulates your skin to regenerate its structural foundation from within, delivering results that develop naturally over weeks and last up to two years or more.

  • Biostimulator Specialist

    Extensive experience with PLLA biostimulators including Alloclae (AestheFill) and Sculptra: Dr. Avaliani understands the precise injection techniques required for optimal collagen stimulation

  • Board-Certified Physician

    11+ years of aesthetic medicine experience. Every Alloclae treatment protocol is personally designed and performed by Dr. Avaliani for safe, predictable collagen restoration

  • Gradual, Natural Results

    Results develop gradually over weeks and months as your body produces new collagen, no one will know you had a treatment, just that you look refreshed and rejuvenated

  • A Reputation Built on Results

    5.0-star rating with 565+ verified patient reviews and proven collagen restoration outcomes with biostimulator treatments

  • Personalized Approach

    Customized biostimulator protocols tailored to your specific volume loss patterns, facial anatomy, and long-term rejuvenation goals

What Is Alloclae?

Alloclae (also known as AestheFill) is a poly-L-lactic acid (PLLA) biostimulator injectable that works by stimulating your body’s own collagen production. Rather than simply filling in volume like traditional hyaluronic acid fillers, Alloclae triggers a natural regenerative process that gradually rebuilds the structural collagen framework beneath your skin, restoring volume, firmness, and youthful contour over time.

At Dr. Avaliani’s practice, every Alloclae session is performed with meticulous precision. The PLLA microspheres are injected strategically into areas of volume loss using advanced technique. Once placed, the microspheres act as a scaffold that stimulates fibroblasts to produce new collagen, gradually restoring the fullness and structure that aging has diminished.

How Alloclae Biostimulation Works

The Alloclae biostimulation protocol follows a carefully designed process:

  • Dr. Avaliani performs a comprehensive facial assessment to map areas of volume loss and collagen depletion
  • Alloclae is reconstituted and precisely injected into the targeted areas using a specialized technique
  • The PLLA microspheres create a scaffold that stimulates your fibroblasts to produce new collagen
  • Over the following weeks and months, new collagen gradually forms, restoring natural volume and firmness
  • A series of 2-3 treatments spaced 4-6 weeks apart builds progressive, long-lasting collagen restoration

Concerns We Treat with Alloclae

  • Facial Volume Loss

    Generalized facial volume depletion from aging, weight loss, or collagen breakdown. Alloclae gradually rebuilds the underlying collagen structure, restoring a fuller, more youthful facial appearance without the overfilled look of traditional fillers.

  • Temple Hollowing

    Sunken, hollow temples that create an aged, gaunt appearance and disrupt facial harmony. Alloclae biostimulation gradually fills the temporal fossa by stimulating collagen production in the deep tissue, restoring smooth, natural contour.

  • Cheek Deflation

    Loss of cheek volume that causes the midface to flatten and sag, creating a tired or aged look. Alloclae restores the cheek mounds’ underlying structural support through gradual collagen regeneration for natural lift.

  • Jawline Definition

    Softened or undefined jawline caused by collagen loss and skin laxity along the lower face. Alloclae rebuilds the collagen foundation along the jawline, restoring definition and a more sculpted profile over time.

  • Hand Rejuvenation

    Thin, bony-looking hands with visible tendons and veins caused by volume and collagen loss. Alloclae stimulates new collagen in the dorsal hand area, gradually restoring plumpness and a more youthful hand appearance.

  • Collagen Depletion

    Overall collagen breakdown from aging, sun damage, or lifestyle factors that leads to skin thinning, fine lines, and loss of structural support. Alloclae addresses the root cause by stimulating your body to produce new, healthy collagen.

Our Alloclae Treatment Options

Dr. Avaliani offers a comprehensive biostimulator approach for optimal collagen restoration. Here’s how Alloclae fits into her treatment portfolio:

  • Alloclae (PLLA Biostimulator)

    A next-generation poly-L-lactic acid biostimulator that stimulates your body’s own collagen production for gradual, natural volume restoration. Results develop over weeks and last up to 2+ years. Ideal for temples, cheeks, jawline, and hands.

  • Complementary: Sculptra®

    Another PLLA-based biostimulator with a long track record of safety and efficacy. Dr. Avaliani may recommend Sculptra as an alternative or complement to Alloclae depending on your specific anatomy and treatment goals. Both stimulate collagen production for long-lasting results.

  • Biostimulator Combination Protocol

    Dr. Avaliani may combine Alloclae with dermal fillers, skin boosters, or other treatments for comprehensive facial rejuvenation. Biostimulators rebuild the deep collagen foundation while complementary treatments address surface texture, hydration, and immediate volume needs.

Call us today to schedule your Alloclae consultation with Dr. Avaliani and take the first step toward gradual, natural collagen restoration!

Does It Hurt?

Your comfort options (we tailor this to you)

Alloclae treatment is well tolerated by most patients. Topical numbing cream is applied before the procedure, and lidocaine is mixed directly with the Alloclae product to minimize discomfort during injection. Most patients describe a mild pressure or slight stinging sensation that subsides quickly. Any injection-site swelling typically resolves within 2-5 days.

Dr. Avaliani prioritizes your comfort at every step. A post-treatment massage protocol is performed to distribute the product evenly and ensure optimal collagen stimulation. You will also be instructed to self-massage the treated areas for several days following the procedure. Pro-Nox (nitrous oxide) is available for patients who prefer additional relaxation during treatment.

Feel Calm. Stay in Control. Look Amazing.

Learn about your comfort options ›
  • Reduced anxietySettle into a calm, relaxed state before and during your treatment, with no stress and no tension.
  • Less discomfortEnhanced comfort for your treatment, so you can focus on your results.
  • No downtimeWalk out feeling great and drive yourself home. No recovery time required.

Is Alloclae Right for Me?

Ideal Candidates

You may be a good candidate if you:

  • Are experiencing facial volume loss from aging, collagen depletion, or weight loss
  • Want gradual, natural-looking results rather than immediate filler volume
  • Are looking for long-lasting collagen restoration that improves over time
  • Have hollowing in the temples, cheeks, jawline, or backs of hands
  • Are in good overall health and willing to commit to a series of 2-3 treatment sessions
  • Want a biostimulator alternative to traditional fillers for a more natural rejuvenation approach

What Does Alloclae Cost?

  • Pricing Information

    The cost of Alloclae treatment depends on the number of vials needed, the treatment areas, and the total number of sessions in your protocol. Price Range: Typically 2-3 sessions spaced 4-6 weeks apart for optimal collagen stimulation During your consultation, Dr. Avaliani will assess your collagen loss, map your areas of volume depletion, and recommend a customized Alloclae treatment protocol with transparent pricing. Results develop gradually and last up to 2+ years, making Alloclae an excellent long-term investment in your appearance.

View before & after gallery

Results vary from patient to patient. The gallery shows real outcomes from treatments performed by Dr. Avaliani.

Before and after imagery to be added for this treatment.

Alloclae frequently asked questions

  • What is Alloclae (AestheFill)?

    Alloclae, also known as AestheFill, is a poly-L-lactic acid (PLLA) biostimulator injectable. Unlike traditional hyaluronic acid fillers that add immediate volume, Alloclae works by stimulating your body’s own fibroblasts to produce new collagen. This results in gradual, natural-looking volume restoration that develops over weeks and months.

  • How is Alloclae different from Sculptra?

    Both Alloclae and Sculptra are PLLA-based biostimulators that stimulate collagen production. Alloclae features a newer formulation with porous PLLA microspheres designed for more uniform collagen stimulation and potentially smoother results. Dr. Avaliani will recommend the biostimulator best suited to your specific anatomy and goals during your consultation.

  • How long do Alloclae results last?

    Alloclae results can last up to 2 years or more. Because the treatment stimulates your body to produce its own collagen, the results are long-lasting and natural. Maintenance treatments can extend results even further. The longevity of results varies based on individual metabolism and the treatment area.

  • How many Alloclae sessions will I need?

    Most patients require a series of 2 to 3 treatment sessions spaced 4 to 6 weeks apart for optimal collagen stimulation. The exact number of sessions depends on the degree of volume loss, the treatment areas, and your individual response. Dr. Avaliani designs a personalized protocol during your consultation.

  • When will I see results from Alloclae?

    Results from Alloclae develop gradually as your body produces new collagen. You may notice initial improvement within a few weeks, with progressive enhancement over 2 to 3 months following each treatment session. The gradual onset means results look completely natural, no one will know you had a treatment.

  • Does Alloclae treatment hurt?

    Alloclae treatment is well tolerated. Topical numbing cream is applied before the procedure, and lidocaine is mixed directly with the product to minimize discomfort. Most patients describe mild pressure or slight stinging during injection. Any swelling or tenderness typically resolves within 2 to 5 days.

  • What areas can be treated with Alloclae?

    Alloclae is commonly used to treat facial volume loss in the temples, cheeks, jawline, and nasolabial folds. It is also effective for hand rejuvenation and other areas where collagen loss has caused volume depletion. Dr. Avaliani will assess which areas would benefit most during your consultation.

  • What is the downtime after Alloclae?

    Downtime is minimal. Most patients experience mild swelling, redness, or tenderness at the injection sites for 2 to 5 days. Bruising is possible but usually minor. You can return to most normal activities the same day. Dr. Avaliani will instruct you on a post-treatment massage protocol to ensure optimal product distribution.

  • Is there a massage protocol after Alloclae?

    Yes. Following Alloclae treatment, Dr. Avaliani will perform a post-treatment massage and instruct you to continue massaging the treated areas at home for several days. This helps distribute the PLLA microspheres evenly and promotes uniform collagen stimulation throughout the treatment area.

  • Who should not receive Alloclae treatment?

    Alloclae is not recommended for patients who are pregnant or breastfeeding, have active skin infections at the treatment site, have a known allergy to PLLA, or have autoimmune conditions that affect collagen production. Patients with unrealistic expectations about immediate results may be better suited for traditional dermal fillers. Dr. Avaliani evaluates each patient individually.

Luxury treatments. Flexible payment options.

Exceptional aesthetic care should be available when you are ready. We offer financing that lets you begin treatment now and manage the cost over time.

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30 East 60th Street, Suite 1100New York, NY, 10022(btw Park & Madison Ave)
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