Restylane® Defyne™
Firm HA Filler with XpresHAn Technology™ for Deep Fold Correction That Moves Naturally
- ExpertiseTop 1%Injector in the country
- ExperienceOver 11,000Patients treated
- Excellence590+Five star reviews
Why Choose Dr. Avaliani for Restylane® Defyne™?
Restylane® Defyne™ is an FDA-approved hyaluronic acid dermal filler designed for correction of deep to severe facial wrinkles and folds in adults over 21. Using XpresHAn Technology™, Defyne’s firm yet flexible gel provides strong structural support while still moving naturally with your facial expressions, correcting deep smile lines and marionette lines without the stiff, overfilled appearance. Results last 6-12 months.
XpresHAn Technology
XpresHAn Technology™ creates a firm yet flexible HA gel with varying particle sizes that corrects deep folds at multiple tissue depths, providing strong support without restricting natural facial movement
Board-Certified Physician
11+ years of aesthetic medicine experience. Dr. Avaliani personally performs every Defyne treatment using Accuvein technology and cannula technique for precise, bruise-free results
Deep Fold Correction
Powerful correction of deep nasolabial folds and marionette lines that other fillers struggle to address, with results lasting 6-12 months and natural expression preserved
A Reputation Built on Results
5.0-star rating with 565+ verified patient reviews and proven deep fold correction that looks and feels completely natural
Personalized Approach
Customized injection plans targeting deep wrinkles and folds while preserving your natural facial movement and expressions
What Is Restylane® Defyne™?
Restylane® Defyne™ (formerly known as Emervel Deep) is an FDA-approved hyaluronic acid filler with XpresHAn Technology™ for deep to severe facial wrinkles and folds. Its firm gel provides powerful structural support while maintaining flexibility, using different particle sizes to correct at multiple tissue depths. Defyne is comparable in use to JUVÉDERM Ultra Plus but with superior expression preservation.
At Dr. Avaliani’s practice, every Defyne treatment is performed with artistic precision using cannula technique for smoother, deeper delivery with minimal bruising. Accuvein technology visualizes blood vessels during injection to virtually eliminate bruising. Defyne’s advanced cross-linking significantly reduces swelling and pain compared to earlier filler generations, making treatment remarkably comfortable even for deep fold correction.
How Restylane® Defyne™ Works
Defyne treatment follows a precise, deep-correction protocol:
- Dr. Avaliani evaluates your deep nasolabial folds, marionette lines, and facial dynamics to design a natural correction plan
- Defyne’s firm XpresHAn gel is precisely injected using cannula technique with Accuvein guidance into deep tissue layers
- The multi-particle gel provides structural support at depth while smaller particles smooth the surface for seamless, natural-looking correction
- The firm yet flexible gel moves with your facial expressions, maintaining a natural look whether you’re smiling, talking, or at rest
- Results are visible immediately and last 6-12 months, with the filler naturally breaking down over time
Concerns We Treat with Defyne™
Deep Smile Lines
Severe nasolabial folds that run from the nose to the corners of the mouth. Defyne’s firm gel provides the structural support needed for deep fold correction while XpresHAn Technology preserves natural movement: you can smile and laugh freely.
Deep Marionette Lines
Pronounced lines running from the mouth corners downward that create a heavy, aged appearance. Defyne’s powerful correction lifts and supports these deep folds, restoring a more youthful jawline and lower face contour.
Lower Face Aging
Significant volume loss and fold formation in the lower face that makes you look older than you feel. Defyne provides the strong support needed to restore lower face structure while maintaining natural-looking results.
Jowl Correction
Pre-jowl folds and early jowl formation along the jawline that soften facial definition. Defyne’s firm gel restores structure along the jawline, creating a more defined and youthful lower face contour.
Chin Creases
Deep horizontal creases and mentalis strain lines on the chin that create a dimpled, textured appearance. Defyne’s firm support smooths and reinforces the chin area for a cleaner, more refined lower face.
Comprehensive Correction
Multiple deep lines and folds requiring substantial correction. Defyne can be combined with Refyne for moderate lines and other Restylane products for a comprehensive rejuvenation that addresses every layer and depth of aging.
Restylane® Defyne™ Details
What makes Restylane® Defyne™ ideal for deep fold correction:
XpresHAn Firm Gel
Defyne’s cross-linking technology creates a firm yet flexible gel specifically designed for deep fold correction. Unlike rigid fillers that restrict movement, Defyne maintains natural facial dynamics while providing the structural support needed for severe wrinkles. Comparable to JUVÉDERM Ultra Plus but with superior expression preservation.
Multi-Depth Correction
Defyne uses varying HA particle sizes to correct at multiple tissue depths simultaneously. Larger particles provide deep structural support while medium particles address mid-level folds and smaller particles smooth the surface. This comprehensive approach is what makes deep corrections look natural, not overfilled.
Extended Duration
Defyne’s firm gel and advanced cross-linking provide results lasting 6-12 months, among the longest-lasting in the Restylane family for lower face correction. The formula is fully reversible with hyaluronidase, providing an important safety advantage. Pro-Nox nitrous oxide is available for additional comfort.
Call us today to schedule your Restylane Defyne consultation with Dr. Avaliani and discover powerful fold correction that still moves naturally!
Does It Hurt?
Your comfort options (we tailor this to you)
Restylane Defyne treatment is very comfortable despite correcting deep folds. The advanced cross-linking technology significantly reduces swelling and pain compared to earlier fillers. Dr. Avaliani uses cannula technique and Accuvein technology for virtually bruise-free results. The Vibrata tool further decreases injection sensation. Pro-Nox (nitrous oxide) is available upon request.
Treatment takes 15-30 minutes. There is minimal to no downtime. Resume normal activities immediately. Mild swelling, if any, typically resolves within a few days. Results are visible immediately and last 6-12 months. The filler is fully reversible and naturally breaks down over time.
Feel Calm. Stay in Control. Look Amazing.
Learn about your comfort options ›- Reduced anxietySettle into a calm, relaxed state before and during your treatment, with no stress and no tension.
- Less discomfortEnhanced comfort for your treatment, so you can focus on your results.
- No downtimeWalk out feeling great and drive yourself home. No recovery time required.
Is Restylane® Defyne™ Right for Me?
Ideal Candidates
You may be a good candidate if you:
- Have deep nasolabial folds or severe smile lines that need strong correction
- Have deep marionette lines or pronounced lower face folds
- Want powerful fold correction that still preserves natural facial expressions
- Need a firmer filler than Refyne for deeper wrinkles and folds
- Are over 21 and want immediate, natural-looking results lasting 6-12 months
- Want a fully reversible treatment with reduced swelling and faster recovery
What Does Restylane® Defyne™ Cost?
Pricing Information
Restylane Defyne pricing depends on the number of syringes needed for your desired correction. Price Range: Results last 6-12 months, with maintenance sessions preserving your deep fold correction During your consultation, Dr. Avaliani will evaluate your folds and wrinkles, discuss your goals, and determine whether Defyne alone or combined with Refyne and other products is ideal. The Aspire Galderma Rewards program may provide additional savings.
View before & after gallery
Results vary from patient to patient. The gallery shows real outcomes from treatments performed by Dr. Avaliani.
Before and after imagery to be added for this treatment.
Restylane® Defyne™ frequently asked questions
What is Restylane Defyne?
Restylane Defyne is an FDA-approved hyaluronic acid filler with XpresHAn Technology designed for deep to severe facial wrinkles and folds in adults over 21. Its firm yet flexible gel provides strong structural support while moving naturally with your facial expressions.
How long do Defyne results last?
Defyne results typically last 6 to 12 months, among the longest-lasting in the Restylane family for lower face correction. The filler naturally breaks down over time as your body metabolizes the hyaluronic acid. Duration varies by individual metabolism.
How is Defyne different from Refyne?
Defyne has a firmer gel for deep folds, while Refyne has a lighter, more flexible gel for moderate wrinkles. Defyne is comparable to JUVÉDERM Ultra Plus, Refyne to JUVÉDERM Ultra. Dr. Avaliani often uses both products together for comprehensive lower face correction.
Does Defyne treatment hurt?
Defyne treatment is very comfortable despite correcting deep folds. The advanced cross-linking reduces swelling and pain compared to older fillers. Dr. Avaliani uses cannula technique, Accuvein technology, and the Vibrata tool. Pro-Nox nitrous oxide is available for additional relaxation.
Will my face look natural with deep fold correction?
Yes. XpresHAn Technology is specifically designed to preserve natural movement even with firm gels. Defyne provides powerful support without the stiff, overfilled look. You can smile, laugh, and talk naturally with correction that is virtually undetectable.
Is Defyne reversible?
Yes. Like all hyaluronic acid fillers, Defyne is fully reversible with hyaluronidase enzyme. If needed, the filler can be dissolved quickly and safely. This reversibility provides an important safety advantage for deep fold correction.
What is the recovery time?
There is minimal to no downtime. Most patients resume normal activities immediately. Mild swelling may occur for a few days but is significantly reduced compared to earlier generation fillers thanks to the advanced cross-linking technology.
Can Defyne be combined with other fillers?
Absolutely. Defyne for deep folds is frequently combined with Refyne for moderate lines, Lyft for cheek volume, Kysse for lips, and Silk for fine perioral lines. Dr. Avaliani designs comprehensive multi-product protocols tailored to each patient.
How many syringes will I need?
Most patients require 1 to 2 syringes of Defyne for deep nasolabial folds. The exact amount depends on your fold depth, facial anatomy, and desired correction. Dr. Avaliani will provide transparent recommendations during your consultation.
What is XpresHAn Technology?
XpresHAn Technology is Galderma’s proprietary cross-linking method that creates flexible HA gels with varying particle sizes. For Defyne, this means a firm gel that still moves naturally with expressions while correcting deep folds at multiple tissue depths simultaneously.
Luxury treatments. Flexible payment options.
Exceptional aesthetic care should be available when you are ready. We offer financing that lets you begin treatment now and manage the cost over time.
