Daxxify

The Longest-Lasting Neuromodulator, Up to 6-9 Months of Wrinkle-Free Results

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  • ExpertiseTop 1%Injector in the country
  • ExperienceOver 11,000Patients treated
  • Excellence590+Five star reviews

Why Choose Dr. Avaliani for Daxxify in NYC?

Daxxify (daxibotulinumtoxinA-lanm) is the first and only peptide-formulated neuromodulator, FDA-approved in 2022. Its breakthrough technology delivers results lasting 6 months on average, with some patients seeing up to 9 months, nearly double the duration of traditional neuromodulators. Dr. Avaliani was among the first NYC providers to offer Daxxify.

  • Early Adopter

    One of NYC’s first providers with extensive Daxxify experience since its FDA approval in 2022

  • Board-Certified Physician

    11+ years of aesthetic medicine experience, every treatment performed by Dr. Avaliani personally

  • Bruise-Free Experience

    AccuVein technology for precise, bruise-free injections

  • A Reputation Built on Results

    5.0-star rating with 565+ verified patient reviews and proven Daxxify results

  • Personalized Approach

    Customized Daxxify dosing accounting for its unique peptide formulation and longer duration

What Is Daxxify?

Daxxify (daxibotulinumtoxinA-lanm) is the newest FDA-approved neuromodulator, representing a breakthrough in wrinkle treatment. Unlike traditional neuromodulators, Daxxify uses a novel peptide technology instead of human serum albumin, resulting in significantly longer-lasting results. Clinical trials demonstrated a median duration of 6 months, with some patients experiencing up to 9 months of wrinkle-free results.

At Dr. Avaliani’s practice, Daxxify is ideal for patients who want fewer treatment visits per year without compromising on natural-looking results. The peptide formulation allows the neurotoxin to bind more effectively to nerve receptors, providing sustained muscle relaxation.

How Daxxify Treatment Works

The Daxxify treatment follows a refined protocol:

  • Dr. Avaliani assesses your facial muscles, wrinkle patterns, and goals to determine if Daxxify’s long-lasting formulation is right for you
  • AccuVein technology maps blood vessels for precise, bruise-free placement
  • Daxxify is injected at 5 strategic sites using the FDA-recommended 40-unit minimum, with additional units as needed
  • The peptide-enhanced neurotoxin binds to nerve receptors, blocking acetylcholine release and gradually relaxing muscles over 3-7 days
  • Full results develop in 10-14 days and last an average of 6 months. Some patients enjoy up to 9 months between treatments

What Daxxify Treats

  • Frown Lines (11s)

    The primary FDA-approved indication for Daxxify. Deep glabellar lines are effectively relaxed for 6+ months per treatment, reducing treatment visits by half.

  • Forehead Lines

    Horizontal forehead wrinkles smoothed with Daxxify’s long-lasting formulation. Fewer treatments per year means consistent, uninterrupted smoothness.

  • Crow’s Feet

    Fine lines around the eyes smoothed for months longer than traditional treatments. Ideal for patients who want extended results between visits.

  • Jawline Slimming

    Masseter muscle reduction with Daxxify’s prolonged effect. Patients enjoy a slimmer jawline for up to 6-9 months per session.

  • Neck Bands

    Platysmal bands relaxed for an extended period, maintaining a smooth, youthful neck between treatments.

  • Preventative Treatment

    Start Daxxify when faint lines first appear to prevent deep wrinkles from forming. Its longer duration makes preventative maintenance easier and more affordable.

Our Daxxify Technologies

Dr. Avaliani uses advanced technologies to ensure every Daxxify treatment is precise, comfortable, and optimized for maximum longevity. Here’s what sets her approach apart:

  • DAXXIFY® (daxibotulinumtoxinA-lanm)

    The first peptide-formulated neuromodulator. FDA-approved 2022. Median 6-month duration, some patients up to 9 months. Uses novel peptide technology instead of human serum albumin for enhanced binding and sustained effect.

  • AccuVein® Technology

    Real-time vein visualization for bruise-free precision with every injection procedure.

  • Extended Duration Protocol

    Dr. Avaliani’s strategic Daxxify dosing optimizes the peptide formulation for maximum longevity. Customized unit counts and placement ensure natural results that last.

Call us today to schedule your Daxxify consultation with Dr. Avaliani and discover the longest-lasting wrinkle treatment available!

Does It Hurt?

Your comfort options (we tailor this to you)

Daxxify injections feel identical to other neuromodulators, virtually painless with ultra-fine needles. The entire treatment takes 10-15 minutes. AccuVein ensures precise placement. No anesthesia needed.

Zero downtime. Resume all normal activities immediately. Avoid exercise, heat, and lying flat for 4 hours. The same post-treatment guidelines apply as with other neuromodulators.

Feel Calm. Stay in Control. Look Amazing.

Learn about your comfort options ›
  • Reduced anxietySettle into a calm, relaxed state before and during your treatment, with no stress and no tension.
  • Less discomfortEnhanced comfort for your treatment, so you can focus on your results.
  • No downtimeWalk out feeling great and drive yourself home. No recovery time required.

Is Daxxify Right for Me?

Ideal Candidates

You may be a good candidate if you:

  • Want the longest-lasting wrinkle treatment available
  • Prefer fewer office visits per year
  • Have moderate to severe frown lines, forehead lines, or crow’s feet
  • Want a neuromodulator with breakthrough peptide technology
  • Are in good health without neuromuscular disorders
  • Seek consistent year-round wrinkle prevention with minimal maintenance

What Does Daxxify Cost?

  • Pricing Information

    Daxxify costs more per session than traditional neuromodulators but lasts significantly longer. When calculated per month, the cost is often comparable. Price Range: Dr. Avaliani provides transparent pricing during consultation Fewer sessions per year means Daxxify can be a cost-effective alternative to treatments requiring visits every 3-4 months. Dr. Avaliani will discuss your specific pricing during your consultation.

View before & after gallery

Results vary from patient to patient. The gallery shows real outcomes from treatments performed by Dr. Avaliani.

Before and after imagery to be added for this treatment.

Daxxify frequently asked questions

  • What is Daxxify?

    Daxxify (daxibotulinumtoxinA-lanm) is an FDA-approved neuromodulator that received approval in September 2022. It is the first and only peptide-formulated injectable wrinkle treatment, using a novel peptide technology instead of human serum albumin to deliver significantly longer-lasting results than traditional neuromodulators.

  • How long does Daxxify last?

    Clinical trials involving over 2,700 adults demonstrated a median duration of 6 months, with some patients experiencing up to 9 months of results. This is nearly double the 3-4 month duration of traditional neuromodulators like BOTOX, Dysport, Jeuveau, and Xeomin.

  • How is Daxxify different from BOTOX?

    Daxxify uses a novel peptide formulation instead of human serum albumin, which is used in BOTOX and other traditional neuromodulators. This peptide technology allows the neurotoxin to bind more effectively to nerve receptors, resulting in approximately twice the duration of results. The molecular technology and manufacturing process are fundamentally different.

  • Does Daxxify hurt?

    Daxxify injections feel the same as other neuromodulators, virtually painless using ultra-fine needles. Dr. Avaliani uses AccuVein technology to guide precise placement and minimize bruising. The entire treatment takes just 10-15 minutes. No anesthesia is needed.

  • How quickly does Daxxify work?

    Most patients notice initial softening of wrinkles within 3-5 days after treatment. Full results typically develop within 10-14 days. The onset is comparable to other neuromodulators, but the duration of results is significantly longer.

  • Is Daxxify more expensive?

    Daxxify has a higher per-session cost than traditional neuromodulators. However, because it lasts approximately twice as long, patients need fewer treatments per year. When calculated on a per-month basis, the cost is often comparable to or even less than maintaining results with shorter-acting products.

  • What areas can Daxxify treat?

    Daxxify is FDA-approved for the treatment of moderate to severe glabellar lines (frown lines between the eyebrows). It is also used off-label for forehead lines, crow’s feet, jawline slimming, neck bands, and other areas where neuromodulators are commonly applied.

  • Is there downtime after Daxxify?

    There is zero downtime after Daxxify treatment. You can resume all normal activities immediately. Dr. Avaliani recommends avoiding strenuous exercise, excessive heat, and lying flat for 4 hours after treatment, the same guidelines that apply to all neuromodulators.

  • Who should not get Daxxify?

    Daxxify should not be used in patients with a known allergy to botulinum toxin products, those with neuromuscular disorders such as myasthenia gravis or Lambert-Eaton syndrome, or women who are pregnant or nursing. Dr. Avaliani will review your full medical history during consultation.

  • Can I switch from BOTOX to Daxxify?

    Yes. Many patients switch from BOTOX to Daxxify to benefit from longer-lasting results and fewer office visits per year. Dr. Avaliani will help determine the ideal timing for your transition based on when your current neuromodulator is due for retreatment.

Luxury treatments. Flexible payment options.

Exceptional aesthetic care should be available when you are ready. We offer financing that lets you begin treatment now and manage the cost over time.

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30 East 60th Street, Suite 1100New York, NY, 10022(btw Park & Madison Ave)
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